Buy Amoxicillin 250mg (amoxicillin trihydrate) Online

Amoxicillin 250mg - Amoxicillin trihydrate information

Amoxicillin 250mg - Pharmacological instruction

According to official guidance on the use of amoxicillin, a drug resistant to the effects of hydrochloric acid gastric juice. Consequently it achieved almost complete digestibility antibacterial active agent.

Caution should be exercised when dosing in mind the possible overdoses by negligence. When injected into the human body tissue starts to actively produce amoxicillin transferase, which is due to the impact of disrupted production of protein compounds in the cell structures of bacteria. This makes it impossible for the reproduction and growth of bacterial flora.

Decomposes with the release of bacterial cells in the blood of a large amount of toxins. This can cause a short-term deterioration of the human condition of the patient in the first 12 - 24 hours after initiation of therapy. 2B amoxicilin-clinical trials revealed adverse effects of the Amoxicillin 250mg on the pathogenic form following:

- Staphylococci strains which do not produce penicillinase;

- Streptococci of all types;

- Salmonella;

- Shigella;

- Klebsiella;

- Other forms of aerobic bacteria.

Taking Amoxicillin 250mg at any time, regardless of food intake. They have no effect on the penetration mechanism of the drug components in the blood stream. Upon receiving the suspension, tablets or capsules maximum amoxicillin concentration level of active ingredient is achieved after 2 h. After 5 hours of amoxicillin found in almost all body fluids and tissues of the human body.

Most available concentrations are formed in the pleural cavity, the pericardial, soft tissues, the alveoli, pulmonary mucosa, oral cavity and bronchi. Easily penetrates into the abdominal cavity, the female genital organs, urine and bile. It defines the possible indications for the use of amoxicillin. unavailable to the antibiotic media are meninges and spinal cord. In these tissues can penetrate only amoxicillin at a concentration of up to 20 percent.

This amount is not enough to affect the pathogens causing encephalitis, meningitis and arhnoidit. In these forms of the disease the drug is not recommended except in extreme cases. Because the body the drug excreted by the kidneys and liver practically unchanged. How to apply for the children to reduce side effects and to prevent the development of the emetic syndrome amoxicillin it is advisable to give children in the form of a suspension, which is prepared on the basis of special granules.

Depending on the prescription takes a certain amount of granules for receiving a single medicament. But most recommended one-stage preparation of suspensions for the entire course of treatment. To this vial pellet water is added at room temperature to a specified level. After vigorous stirring a homogeneous suspension is obtained, which is the shelf life of 12 days. Store should be in a cool dark place. Before the use of re-stirred and is measured using a special dispenser, which included drug packaging


Use amoxicillin trihydrate while angina

Angina only after preliminary seeding material obtained during the intake stroke of the throat. The active ingredient of the drug is a stimulant substance for the rapid growth of diphtheria bacilli. This can be a fatal mistake, which will result in the patient's death. Especially it concerns an indication of young children who are exposed to diphtheria lesions of the tonsils and throat.

With the exclusion of diphtheria and sensitive detection of the bacterial microflora types amoxicillin trihydrate angina appointed under the standard scheme:

5 days - treatment;

single dose - 500 mg in adults and in children 250 mg;

4 daily required dosage.

Can I use it while pregnancy?

In the breastfeeding period amoxicillin is absolutely contraindicated. In pregnancy, the drug can be used only under the constant supervision of the physician. Other contraindications to the rest of the contraindications for the use of amoxicillin include kidney and liver failure.

You can not use amoxicillin trihydrate antibiotic at:

- asthma;

- hemodyscrasia functions;

- leukemia and limfozah;

- hypersensitivity to penicillin individual character row drugs.

In the presence of contra-appointed analogue amoxicillin trihydrate. This can be ampiox, flemoxin, ampicillin selection at the doctor.

Amoxicillin trihydrate Dosage and Administration

The capsules are taken orally without chewing entirely before or after meals, drinking plenty of water.

Adults administered at 500 mg three times a day.

In severe disease - 1 g 3 times a day.

Children aged 5-10 years appoint 250 mg 3 times a day. The course of treatment - 5-12 days.

For the treatment of uncomplicated gonorrhea prescribe a single dose of 3 g (1 g simultaneously administered probenecid). Women are recommended to repeat this dose a day.

Patients with end-stage renal failure (creatinine clearance <10 mL / min), the dose of amoxicillin should be reduced by 15-50% or increase the interval between doses of up to 24 hours.

Amoxicillin trihydrate Side effects

• From the gastrointestinal tract: rarely - diarrhea, itching in the anus; possible indigestion; in some cases - pseudomembranous colitis and hemorrhagic.

• From the urinary system: rarely - the development of interstitial nephritis.

• From the side of hematopoiesis: rarely - agranulocytosis, thrombocytopenia.

• Allergic reactions: skin reactions, mostly in the form of specific maculopapular rash; rarely - erythema multiforme, Stevens-Johnson syndrome; in some cases - anaphylactic shock, angioedema.

Amoxicillin 250mg Contraindications:

• hypersensitivity to the drug and other beta-lactam antibiotics;
• infectious mononucleosis and lymphatic leukemoid reaction type.

Pregnancy and lactation

Information about a possible embryotoxic, teratogenic or mutagenic effects of the drug while taking during pregnancy are not currently available.
Amoxicillin is found in breast milk, which should be considered when assigning Amoxicillin during lactation.


Symptoms include nausea, vomiting, diarrhea, disruption of water and electrolyte balance (as a result of vomiting and diarrhea).

Treatment: gastric lavage, activated charcoal, saline laxatives, drugs to maintain water and electrolyte balance.

Precautionary measures.

In exchange treatment is necessary to monitor the state functions of blood, liver and kidneys. Perhaps the development of superinfection due to growth insensitive to it microflora, which requires a corresponding change in antibiotic therapy. When treating patients with bacteremia may develop bacteriolysis reaction (Jarisch-Herxheimer). In patients with increased sensitivity to penicillins, possible allergic cross-reaction with cephalosporin antibiotics. Treatment continues for sure 48-72 h. After the disappearance of clinical signs of disease.

Interaction with other meds

Probenecid, phenylbutazone, oskifenbutazon, to a lesser extent - acetylsalicylic acid and sulfinpyrazone tubular secretion suppressing drugs penicillins, which leads to increased half-life and amoxicillin concentration in the blood plasma.

Amoxicillin is valid only for breeding microorganisms, so it should not be administered concurrently with antimicrobials acting bacteriostatic.

In the presence of positive tests for the sensitivity of the pathogen amoxicillin can be used in combination with other bactericidal antibiotics (cephalosporins, aminoglycosides).

Shelf life.

Store in a dry and dark place at a temperature not exceeding 25 ° C.
Shelf life.

3 years.

Do not use the drug after the expiry date.

Conditions of supply.

By prescription.


10, 20 or 30 capsules in polymeric cans for packaging drugs. A bank or 1, 2 or 3 blisters with instruction in the secondary packaging of cardboard boxed.